Biomedical Technology Resources
Collaboration Through Dissemination
Download Back


Supported Platforms

Linux, Mac OSX, Windows

Supported Data Formats


Resource Description

ProDy is a free and open-source Python package for protein structural dynamics and sequence evolution analysis. It is designed as a flexible and responsive API suitable for interactive usage and application development. NMWiz, a VMD plugin GUI, also accompanies ProDy for streamlining protein dynamics analysis calculations and enabling comparative visual analysis of experimental and theoretical data.
With ProDy, you can perform principal component analysis of heterogeneous X-ray structures, NMR models, and MD snapshots. Protein dynamics can be modeled using normal mode analysis of anisotropic network model with optional distance and property dependent force constants. Powerful and customizable atom selections allow for contact identification and matching, superposing, and comparing multiple structures/chains. Newest additions to ProDy include fast and flexible features for analysis of sequence evolution and its comparison to protein functional dynamics.