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Center for Functional Imaging Technologies

Bruce R. Rosen, Ph.D.
P41EB015896
Active

Center Overview

The Center for Functional Neuroimaging Technologies is a Regional Resource located at the Athinoula A. Martinos Center for Biomedical Imaging at the Massachusetts General Hospital. Working within the integrated multimodal imaging environment of the Martinos Center, the goal of the Resource is to develop and apply innovative neuroimaging technologies and techniques to enable closer examination of the human brain, and thereby contribute to better understanding of the brain in health and disease. To this end, we seek to develop new techniques and advance existing technologies for acquisition and analysis of functionally specific images of the working brain, with unprecedented physiological precision and spatiotemporal resolution. The research and development aims to improve and extend existing methods for noninvasive magnetic resonance image analysis and acquisition, electromagnetic source imaging, optical neuroimaging, and most recently, combined MR-PET neuroimaging. The Resource provides an essential interactive environment, within which an interdisciplinary team of highly skilled scientists, engineers, and clinicians with diverse expertise in multiple modalities and disciplines. The resource supports service use of the Center's facilities by neuroscientists throughout the country, provide extensive training opportunities for students, fellows, and staff scientists, and seek to advance the field of brain mapping through active dissemination of new knowledge and technology.

Impact on Human Health

The Resource, by actively developing cutting-edge neuroimaging technologies, conducting collaborative research involving applications of these technologies, and extending them for service use to the broader neuroscientific research community, has extensive potential to help shape the basic neuroscience and translational research landscape. Ultimately, this work may thus facilitate the development of new therapeutic advances for an astounding array of neurological and psychiatric diseases.

Resources

ResourceDescriptionSupported PlatformsSupported FormatsData TypeData Size (compressed)
APU
Center for Functional Imaging Technologies
NIBIB

APU (Atlas-guided Photon-migration Utilities) provides utilities for using a structural MRI (from an atlas or any other MRI) to guide the analysis of Near Infra-Red Spectroscopy (NIRS) data. These tools are used in conjunction with FreeSurfer and MNE.

Linux, Mac OSX, Windows AFNI, DICOM, GIFTI, MGZ,...(more) N/A N/A
Array Sensitivity Metric Software
Center for Functional Imaging Technologies
NIBIB

This reconstruction program runs on the Siemens scanner generating Dicom images of the array SNR computed with the Optimum method (uses noise correlation matix) and Sum of Squares (SoS).

N/A N/A
Freesurfer & FS-Fast
Center for Functional Imaging Technologies
NIBIB

The FreeSurfer package is a suite of tools for segmentation, registration, surface reconstruction and processing of general neuroanatomical models of the human brain. It includes FS-Fast fMRI data analysis tools. (Freesurfer Wiki)

Linux, Mac OSX, Windows AFNI, DICOM, GIFTI, MGZ,...(more) N/A N/A
HF-1
Center for Functional Imaging Technologies
NIBIB

An Open-Source Hardware and Software Platform for Simultaneous Electrophysiology and MRI

Windows ascii, Binary, RAW N/A N/A
HomER
Center for Functional Imaging Technologies
NIBIB

HomER (Hemodynamic Evoked Response) graphical interface for visualization and analysis of Near Infra-Red Spectroscopy (NIRS) data.

Linux, Mac OSX, Windows N/A N/A
iso2mesh
Center for Functional Imaging Technologies
NIBIB

iso2mesh is a free matlab/octave-based mesh generation and processing toolbox. It can create 3D tetrahedral finite element (FE) mesh from surfaces, 3D binary and gray-scale volumetric images such as segmented MRI/CT scans.

Linux, Mac OSX, Windows ABAQUS, ASC, COMSOL, DXF,...(more) N/A N/A
MCX
Center for Functional Imaging Technologies
NIBIB

Monte Carlo eXtreme (MCX) is Monte-Carlo simulation software for modeling photon migration in 3D turbid media. Using GPU-based massively parallel computing techniques, it is hundreds times faster compared to traditional CPU-based simulation.

Linux, Mac OSX, Windows JSON N/A N/A
MMC
Center for Functional Imaging Technologies
NIBIB

Mesh-based Monte Carlo, or MMC, is a Monte Carlo (MC) solver for photon migration in 3D turbid media. MMC can represent a complex domain using a volumetric mesh, thus giving better accuracy and computational speed.

Linux, Mac OSX, Windows JSON N/A N/A
MNE
Center for Functional Imaging Technologies
NIBIB

Software for anatomically and functionally constrained MEG/EEG source modeling. Includes tools for preprocessing, forward and inverse modeling, time-frequency analysis, connectivity, and statistics. MNE-C (compiled), MNE-Matlab and MNE-Python (toolboxes)

Linux, Mac OSX, Windows EEG, fif, MEG N/A N/A
OPTseq2
Center for Functional Imaging Technologies
NIBIB

optseq2 is a tool for automatically scheduling events for rapid-presentation event-related (RPER) fMRI experiments (the schedule is the order and timing of events)

Linux, Mac OSX, Windows AFNI, DICOM, GIFTI, MGZ,...(more) N/A N/A
PMI Toolbox
Center for Functional Imaging Technologies
NIBIB

Photon Migration Imaging (PMI) Toolbox for solving diffuse optical imaging (DOI) forward and inverse problems.

Linux, Mac OSX, Windows Matlab N/A N/A