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Laser Microbeam and Medical Program

Bruce J. Tromberg, Ph.D.
P41EB015890
Active

Center Overview

The Laser Microbeam and Medical Program (LAMMP), is dedicated to the use of lasers and optics in biology and medicine. LAMMP is located within the Beckman Laser Institute, an interdisciplinary biomedical research, teaching, and clinical facility at the University of California, Irvine. The overall objective is to promote a well-balanced BTRC with activities in technological research and development, collaborative research, service, training, and dissemination. One of the primary goals of LAMMP is to facilitate "translational" research by rapidly moving basic science and technology discoveries from "blackboard to benchtop to bedside". This is accomplished by combining state of the art optical technologies with specialized resource facilities for cell and tissue engineering, histopathology, pre-clinical animal models, and clinical care. The resource center has been organized into 3 cores:

  1. Microscopy and Microbeam Technologies (MMT) for high-resolution functional imaging and manipulation of living cells and tissues
  2. Medical Translational Technologies (MTT) for non- and minimally-invasive monitoring, treating, and imaging pre-clinical animal models and human subjects, and
  3. Virtual Photonics Technologies (VPT) for developing computational models and methods that advance the performance of biophotonic technologies, and enhance the information content derived from optical measurements.

LAMMP cores contain complementary technologies that are capable of quantitatively characterizing, imaging, and perturbing structure and biochemical function in cells and tissues with scalable resolution and depth sensitivity ranging from micrometers to centimeters.

Impact on Human Health

LAMMP technologies are relevant in areas such as cancer, cardiovascular disease, metabolic syndrome, and neurologic function, as well as fundamental biological process, such as mechano-transduction, wound repair, angiogenesis, fibrosis, and cell death.

Resources

ResourceDescriptionSupported PlatformsSupported FormatsData TypeData Size (compressed)
Virtual Tissue Simulator (VTS)
Laser Microbeam and Medical Program
NIBIB

A modular and scalable platform to provide an integrated suite of computational tools to define, solve, visualize, and analyze relevant forward and inverse radiative transport problems in Biomedical Optics.

Linux, Mac OSX, Windows N/A N/A